Antibody-secreting cells (ASC), plasmablasts and plasma cells, are terminally differentiated B cells responsible for large-scale production and secretion of antibodies.ASC are derived from Rolling Machines activated B cells, which may differentiate extrafollicularly or form germinal center (GC) reactions within secondary lymphoid organs.ASC therefo
Bacterial xenogeneic silencing proteins selectively bind to and silence expression from many AT Cushion rich regions of the chromosome.They serve as master regulators of horizontally acquired DNA, including a large number of virulence genes.To date, three distinct families of xenogeneic silencers have been identified: H-NS of Proteobacteria, Lsr2 o
Altitude and ultraviolet (UV) radiation may affect the community composition and distribution of microorganisms in soil ecosystems.In this study, 49 soil samples from 10 locations were collected from different elevations on the eastern Pamir Plateau and analyzed for soil microbial community structure and function using high-throughput sequencing.Th
In 2002, the first crop genome was published using the rice cultivar 93-11, which is the progenitor of the first super-hybrid rice.The genome sequence has served as a reference genome for the indica cultivars, but the assembly has not been updated.In this study, we update the 93-11 genome assembly to a gap-less sequence using Sweatshirt ultra-depth
Johanson-Blizzard syndrome (JBS; OMIM 243800) is Custom Sweatshirt an autosomal recessive disorder that includes congenital exocrine pancreatic insufficiency, facial dysmorphism with the characteristic nasal wing hypoplasia, multiple malformations, and frequent mental retardation.Our previous work has shown that JBS is caused by mutations in human